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Postdoc in Autoimmunity

Aarhus University
Aarhus, Region Midtjylland
Full time
for 1 dag siden
The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position as Postdoc in the field of Autoimmunity as per 1 November 2025 or as soon as possible thereafter. The position is a fixed-term full-time position for 27 months.

The Department of Biomedicine prioritises diversity and a good work environment, as this is a prerequisite for groundbreaking research. In a diverse and international research environment, dedicated employees are looking to generate new knowledge within biomedical research areas such as infection and inflammation, membranes, neuroscience and personalised medicine. The Department of Biomedicine provides research-based teaching of the highest quality and is responsible for a large part of the medical degree programme. Academic staff contribute to the teaching. English is the preferred language in the laboratory, at meetings and at seminars. The department employs approx. 500 people from all over the world, and they make use of the department's modern laboratory-, core- and animal facilities. The Department of Biomedicine focuses on innovation, entrepreneurship and collaboration with business and industry, and numerous researchers from the department have established companies to develop new medicinal treatments founded in professional scientific basic research.

About the research project

Autoimmune connective tissue diseases cover a broad range of autoimmune rheumatic diseases, all characterised by autoantibodies directed towards intracellular antigens. Autoantibodies have been linked to these diseases for decades. This project aims to establish human autoantibody clones from various autoimmune diseases, with a primary focus on Systemic Sclerosis. This is with the purpose of identifying novel mechanisms involved in how autoantibodies interact with intracellular antigens and the inflammatory processes that arise from this interaction.

The host laboratory

The laboratory of Associated Professor Stinne Ravn Greisen and Professor Bent Deleuran is interested in understanding early immune responses induced by autoantibodies, with a focus on connective tissue diseases. We use a broad range of experimental systems, ranging from molecular screening tools, state-of-the-art methods for molecular/cellular characterization, animal models, and primary human cell/organoid models. We offer a unique environment to perform this project with multidisciplinary research teams and expertise in translational approaches, thus allowing us to fully develop the project from gene identification, via mechanistic exploration, to the characterization of the autoantibodies’ pathogenic role in vivo.

Our core values are high ambitions, a collaborative and friendly culture, and development of talent.

Your job responsibilities

As Postdoc in Autoimmunity your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality. In your daily work, you will work closely with colleagues on your project, where you will receive supervision and guidance.

Your main tasks will consist of:
  • Independent research of high international quality, including publication.
  • Single cell RNA sequencing and data analysis
  • Characterization and production of monoclonal antibodies
  • Flow cytometry
  • Confocal microscopy
  • qPCR
  • In vitro cell cultures
  • Organoid model culturing
  • Mouse model optimization and validation

You will report to the Professor Bent Deleuran and Associate Professor Stinne Greisen

Your competences

You have academic qualifications at PhD level, for example within the following areas of autoimmunity or immunology, and have experience with autoantibodies, cell work, and RNA sequencing. Alternatively, you have significant experience with large screening setups and are highly motivated to apply this expertise to solve a question in autoimmunity and immunology.

Specifically, skills in management and development of innovative research projects to the highest level, antibody characterization, including single cell RNA sequencing and of their antigen-binding sites, and Qualitative analysis and interpretation of RNA sequencing data are desirable. We also prefer is you have experience with Production of monoclonal antibodies, biochemical and cell biological assays in immunology with a focus on DNA and RNA nucleotide sensing, quantitative confocal microscopy, Flow cytometry and qPCR.

As a person, you have good interpersonal skills, are inclusive and team-oriented and able to contribute to a good work environment. We expect you to be fluent in oral and written English.

In order to be assessed as qualified for a Postdoc position, you must meet these academic criteria.

Shortlisting will be used.

Questions about the position

If you have any questions about the position, please contact Bent Deleuran tel.: (+45) 51725158 or Stinne Greisen tel.: (+45) 22451114 .

Your place of work will be the Department of Biomedicine, Bartholin Building, Wilhelm Meyers Alle 4, DK-8000 Aarhus C, Denmark.

We expect to conduct interviews in week 36/37.

Terms of employment

  • Appointment as a postdoc requires academic qualifications at PhD level.
  • Further information on the appointment procedure can be found in the Ministerial Order on the Appointment of Academic Staff at Universities.
  • The appointment is in accordance with the Danish Confederation of Professional Associations (Akademikerne).
  • Remuneration is in accordance with the above, and the Salary agreement catalogue for staff at Health.
  • The yearly base salary for a fulltime postdoc is between DKK 484.214,84 and DKK 538.720,20 depending on the years of working experience after achieved MSc degree. The base salary includes a position related supplement and pension (17.1 %). Additional supplement(s) for special qualifications can be negotiated. Authorisation supplemement(s) will be granted, if relevant for the position. Your local eligible trade union representative at Aarhus University negotiates your salary on your behalf.
  • Researchers recruited from abroad are offered a special researcher tax scheme with a lower tax rate.
  • Further information on qualification requirements and job description can be found in the Ministerial Order on Job Structure for Academic Staff


Application

Your application must include the following:
  • Motivated application
  • Curriculum Vitae
  • Diploma
  • Template for applicant - postdoc
  • A list of publications
  • A teaching portfolio. We refer to Guideline on the use of teaching portfolios
  • A maximum of five of the publications of greatest relevance to the job may be submitted (optional)
  • Research plan can be uploaded (optional)
  • Coauthor statement(s) can be uploaded (optional)
  • References/recommendations can be uploaded separately in the e-recruitment system (optional)
We refer to the faculty’s Guidelines for applicants.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.


International applicant?

Aarhus University offers a broad variety of services for international researchers and accompanying families, including assistance with relocation and career counselling to expat partners. Please find more information about the International Staff Office and the range of services here. Aarhus University also has a Junior Researcher Association and offers career development support.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.
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