We are seeking an outstanding scientist with a strong track record in single-cell biology, especially single-cell proteomics, to join the Section for Medical Biotechnology, embedded in the Department of Biotechnology and Biomedicine, Technical University of Denmark.
This position offers a unique opportunity to lead cutting-edge research at the forefront of single-cell resolution biology and to drive innovation in understanding complex mammalian systems. The successful candidate will be expected to provide visionary leadership and establish an internationally competitive research group focusing on the development and application of advanced proteomics, multi-omics, and computational strategies to explore cellular heterogeneity across both healthy and diseased stem-cell hierarchies. Your research will integrate systems biology and data science to unravel the protein-level mechanisms underlying cell differentiation and malignant transformation. In addition, you will pioneer next-generation molecular workflows for single-cell and spatial omics to investigate stem cell dynamics, disease heterogeneity, and intricate cellular interactions across space and time.
Responsibilities and qualifications
The successful candidate will be expected to lead an ambitious, and internationally competitive research program that advances the frontiers of single-cell technologies, with a focus on disease biology and the complex protein networks that govern cell fate and function. A strong commitment to mentoring the next generation of scientists and fostering interdisciplinary collaboration is essential. The candidate should bring a clear vision for applying advanced single-cell technologies, particularly single-cell proteomics by mass spectrometry (scp-MS), to investigate cellular heterogeneity in both healthy and malignant cellular systems.
The research strategy is expected to include the development of novel computational methods to analyze high-dimensional data, as well as the application of in vivo model systems to complement in vitro approaches for modeling stem cell dynamics. You will also be expected to take an active role in strengthening the Department’s activities within the context of the Technical University Hospital (TUH), where we are breaking new ground in areas like clinical proteomics, patient diagnostics and automation. This role provides an opportunity to shape the future of proteomics by pushing methodological boundaries and delivering fundamental biological insights.
You will collaborate with other department faculty members to make further development of the engineering educations within our biochemistry, immunology and pharma technology activities, by developing and supporting new pedagogical teaching elements and by integration of new research activities into the curriculum of the existing and planned study programs at the bachelor, master and PhD level. Your research activities are expected to link to other relevant engineering areas in the department and the new professor is expected to engage in collaborative projects with groups in the department and relevant DTU departments (e.g. DTU Health, DTU Food, DTU Biosustain). The aim will be to complement existing competences at DTU and create synergies with state-of-the-art methodologies for biomarker identification and studies of biological complexity at single-cell level resolution, thereby advancing existing research agendas and creating new ones.
The successful candidate will have obtained well-documented international recognition within one or more of the above-mentioned research themes. Track record in developing patentable technology will be considered an asset. It is required that you have documented experience as an independently capable researcher within single-cell proteomics, and have extensive experience in establishing, and applying mass spectrometry workflows to complex biological questions. Given the significant amounts of data that will need to be generated and processed, a strong computational background will be viewed favorably. More specifically, you are expected to strengthen activities within the following areas:
- Establishing high-throughput, state-of-the-art single-cell proteomics and multi-omics workflows
- Deciphering cellular complexity in heterogeneous, (cancer) stem cell biology-relevant model systems
- Development of computational frameworks for modelling highly multi-dimensional single-cell data
You are expected to take a lead role in teaching at the BEng, BSc, MSc and PhD levels.
DTU employs two working languages: Danish and English. You are expected to be fluent in at least one of these languages, and in time are expected to master both.
You will be assessed against the responsibilities and qualifications stated above and the following general criteria:
- Documented experience and quality of teaching and curriculum development
- Research impact and experience, funding track record and research vision
- International impact and experience
- Societal impact
- Innovativeness, including commercialization and collaboration with industry
- Leadership, collaboration, and interdisciplinary skills
- Communication skills
Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.
Further information
Further information may be obtained from Head of Department Bjarke Bak Christensen bbch@dtu.dk or Professor Susanne Brix Pedersen Susanne Brix Pedersen sbrix@dtu.dk , tel.: +45 21604264.
You can read more about DTU Bioengineering at www.bioengineering.dtu.dk.
If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.
Application procedure
Your complete online application must be submitted no later than 12 September 2025 (23:59 Danish time).
Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:
- Application (cover letter) addressed to the President
- Vision for teaching and research
- CV including employment history, list of publications indicating scientific highlights, H-index and ORCID (see http://orcid.org/)
- Teaching portfolio including documentation of teaching experience
- Academic Diplomas (MSc/PhD)
You can learn more about the recruitment process here.
Applications received after the deadline will not be considered.
All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position.
The Department of Biotechnology and Biomedicine (DTU Bioengineering) is an international leader in the areas of biotechnology and biomedicine. Our engineering approach to all aspects of biotechnology and biomedicine positions us as a valuable player with unique competences in a growing bio-based economy and with health systems transforming towards personalized medicine. We have a clear focus on the needs in the life science- and biotech industries and point towards innovation, new businesses, and scientific services for the benefit of society. The department has extensive collaborations with national and international research units and industry. DTU Bioengineering has approx. 400 employees, of which 2/3 are scientific staff. The department is located at DTU Lyngby Campus.
Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.